Hypotension Investigation, Prospective Clinical Study

Ian Piper, Alfonsas Vainoras, Kristina Berskiene, Rimtautas Ruseckas, Vidmantas Jurkonis, Liepa Bikulciene, Zenonas Navickas, Dovile Karaliene, Arminas Ragauskas, Mantas Deimantavicius


Hypotension occurring in the initial phase of resuscitation is significantly associated with increased mortality following brain injury, even when episodes are relatively short. A large amount of data exists in health care systems providing information on the major health indicators of patients in hospitals. It is believed that if enough of these data could be drawn together and analysed in a systematic way, then a system could be built that will trigger an alarm predicting the onset of a hypotensive event. In the paper the mathematical information algorithm based on the concept of the rank of a sequence is presented. For the analysis of hypotension physiology an application of a new algebraic method is proposed for real world time series analysis. Numerical experiments with a hypotension crisis prevention using arterial blood pressure time series are used to illustrate the potential of the proposed method. The algorithm for finding ranks of a sequence of the ECG parameters is presented in the paper in order to show complexity profiles. Experimental results show that presented in this paper method also can be used together with other hypotension prediction methods.

DOI: http://dx.doi.org/10.5755/j01.eie.22.2.13454


Hypotension physiology; time series; Hankel atrices; rank; complexity profile.

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